Your situation reminds of what I went through with my first Maltese Rosebud, then Kallie, then Catcher... in other words.... he is acting just like a typical Maltese puppy!
Since Catcher was a puppy more recently I can recall his situation most clearly. I just loved on him even more and made him feel safe. I think they get where they are unsure of things and their surroundings... I thought he was Cujo and where was my sweet puppy. I even looked up info on the Internet about "aggressive dogs". Then whoa... hold on... I remembered that Rosebud and Kallie were the same way, etc. when they were his age. And he wasn't aggressive... he was just a puppy!!
So, I cuddled him more and talked sweet to him and held him more. He responded by being sweeter than ever and I swear I noticed in a few days that he was Cujo no more.
OK... the toilet paper thing.... mine still do that and Kallie is almost 3. The cure is just take it off the roll and put in on the tank where they can't get it. For some reason Malts love paper!
And yep, mine run when I go to pick them up if they think it is time for me to leave or something like that. Please make sure to NEVER EVER scold or do anything negative after you've caught him. Make him associate being "caught" with something good. Even though I am at my wit's end sometimes if one of mine pulls this "trick", I cuddle them when I pick them up. If they associate being caught with something negative, you'll just scare him and he'll keep running. Lots of times, I just start running toward the bedroom and they follow and then I quickly shut the door, but I don't make a big deal out of it... I have finally taught Kallie to sit and wait for me to pick her up... which work about 90% of the time. With Catcher I have to just surprise him and pick him up when he isn't expecting it.
I know the frustration you feel with him biting at your hands and feet, etc. When Catcher would bite my feet, I would just keep walking and ignore it totally. It wasn't fun for him so he soon quit. And since he would bite a lot when we played on the floor, I quit playing on the floor with him for a couple months. I would sit in a chair and throw the ball, etc. Now that he is nine months, he is fine when we play.
I like JMM's idea of the time out but don't be "mean" about it....or make it seem like punishment... just put him in his crate with a toy. I know that sometimes we need a break from our puppies ....
I hope some of this can be useful for you and improve your situation.