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Lola may be relapsing :-( (update on # 75)

6306 Views 82 Replies 53 Participants Last post by  maggieh
Lola started to look a little dull over this past weekend. I didn't think she needed an emegency visit over the weekend. But on Monday morning she started to have gait problems. So off the ASG we go to see Dr. Sullivan. She was actually due to have her regular pre-cytosar check this week anyway. When I get her there, they tell me she has a 104 temp. I feel like a total bad Mommy for not even thinking of taking her temp! So, they did some labs inhouse to see if it was an infection, but...inconclusive. No elevated WBC's, but she may not be able to mount a WBC defense at this point. Urine is out to the outside lab. So, we discuss the likelihood of GME relapse vs. infection. I decided that I want to try to treat infection for 48 hrs. and see if we can get her looking better. So, I take her home with Clavamox. She looked a little perkier when we got home, and she ate her full feeding of food and drank some water, and pee'd in the middle of the kitchen floor. (she gets a pass under the circumstances) She gets settled in her favorite spot on the couch. And then low and behold she tips over and has a big seizure! Scared me to death! My local Vet was in his office, so off we go again. She gets an IV dose of Valium. (can you say drunken salior) She made it through the night. She looks a slight bit perkier today. Still eating and drinking. Temp is down. But I don't know. She still is not 100% with her gait. Kind of slow and a little stumbly (valium still?) But she is WAY off her mark from where she was even a week ago! I am so bummed. Don't know what to expect. Back to pred again?? I just don't know if I can keep doing this to her. Please send prayers and good thoughts for Lola. My sweet girl isn't even 4 years old. This is a dispicable disease!
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i just came on to browse and saw this thread. i hope it is only a minor setback and she gets back on the road to recovery. she is lucky to have you and her great vets to take care of her. hang in there! feel free to msg me if u need ne thing!
Just read the thread Pam, I am sending you good thoughts and prayers to you and Lola. The little steps and every day it will get better and better I know she will bounce back in no time. Hugs and Kisses from Max
Oh Pam, I am so sorry and will be praying so hard for Lola. Bless you both.
Just seeing this now too. Sending massive prayers for our darling Lola.
Pam........how is Lola doing this afternoon?? Praying she is better!! Let us know when you can......:wub:
I hope Lola gets well soon! I had a maltese the had GME also but we couldn't stop the seizures on her. I even too her to Auburn vet school and then couldn't do anything for her, so I know how you feel!
Pam,

Hope Lola is feeling better this afternoon. I know how hard it is to
deal with another medical issue.... but hang in there. We're here
for you.

Hugs.
Debbie
So, I talked at length with Dr. Sullivan this morning. There is no indication in any of Lola's labs that she has an infection. So, that means this is a re-lapse of her encephalitis. So, we are back on prednisone. I went home from work to give her a dose ASAP. We will give her a somewhat high dose over the weekend, and try to get the inflamation under control. I will go for a visit next week, and we will try some new meds. Lola has not tolerated any of the stronger meds real well, so this will be a trial to see if we can improve her situation. But, we also had some of the "hard talk" that if she dosen't respond well, it may be the end fo the line. And I am concerned about her quality. She has become snarly. She growls a little when you pick her up. She was snippy at the vet tech when they took her blood, and she has never done that before (she was always thier favorite due to her sweet nature) and when I took the bandage off, she actually tired to bite me! This is not my girl. I know though that encephalitis probably means she has a big big headache. Hopefully the pred will relieve this quickly. And really hoping that any new meds will be tolerated well. I am not ready to throw the towel in for Lola. But, I will not make her suffer if we are not making progress. Sad.
:crying:
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Oh, I can't even come close to imagining the pain you must be going through! I just saw this thread and I'm hoping hard for a recovery. I'm so sorry you all have to go through this. Hugs to everyone.
I'm sorry, Pam. It's so hard. Praying for you and for Lola.
:smcry: Pam, so very hard. I'm writing this thru tears. I really hope these meds will work. I'm sure that Lola's snarliness is from being poked and prodded so much and feeling crappy and I know prednisone makes them crazy too so that can be more piled on. I'd snarl too. I know you want to do what's best for her and hope the meds will turn around her latest bout. Otherwise I agree that if she's miserable it's hard to see them not enjoy even the simple pleasures in life and be in pain. I'm praying that she'll respond and not throw in the towel either. How did she get encephalitis in the first place...insect bite? Not knowledgeable about that (and other things). You sound like you have an awesome doctor in Dr. Sullivan. You're blessed. Sending hugs to both of you from both of us.:grouphug:
Just read your update... so sorry to hear.. When Harry was not feeling well, he would bite me when I went to remove his bandages or touch him in the wrong way or area, too.... I think they don't know what else to do and that they're scared. I feel so bad for you and Lola... I'll pray that the meds work to help her.

:grouphug::grouphug::grouphug:
Debbie
I'm so sorry Lola is not out of the woods yet. I'll keep her in prayer and hope for improvement.
Pam, I am so sorry to hear Lola is not feeling well. I hope and pray she perks up again soon. You are doing all you can and are a great Mommy!
Oh, gosh, my heart goes out to you and Lola. I remember when my first Malt Rosebud (RIP) was not doing well and her personality was not the same, either. I sure hope the medicines kick in and help your darling little girl. :grouphug:
Oh Pam how I pray the meds help her soon. It's so hard to watch
the little ones suffer, you'll do what 's best for her. Sending hugs and prayer your way.
Pam, I hope Lola improves. It is so hard to watch them suffer. We all know you are doing everything possible to help your sweet Lola. Our thoughts and prayers are with you.
:smcry: Pam, so very hard. I'm writing this thru tears. I really hope these meds will work. I'm sure that Lola's snarliness is from being poked and prodded so much and feeling crappy and I know prednisone makes them crazy too so that can be more piled on. I'd snarl too. I know you want to do what's best for her and hope the meds will turn around her latest bout. Otherwise I agree that if she's miserable it's hard to see them not enjoy even the simple pleasures in life and be in pain. I'm praying that she'll respond and not throw in the towel either. How did she get encephalitis in the first place...insect bite? Not knowledgeable about that (and other things). You sound like you have an awesome doctor in Dr. Sullivan. You're blessed. Sending hugs to both of you from both of us.:grouphug:
GME (Granulomatous Meningo Encephalomyelitis) is a neurologic disease effecting dogs, most commonly small breeds, usually in females. Most effected are Pugs and sometimes it is called Pug encephalitis. There is a more severe form called Necrotizing Meningo Encephalomyelitis that is sometimes called Maltese Encephalitis. GME can be caused by infection, and in the diagnostic stage all dogs are cultured, along with a spinal tap and MRI. If the cultures are pos., the treatment is antibiotics. If neg, it is assumed that it is auto immune mediated. In other words the dogs immune system is attacking the dog. The only true diagnosis can be made at necropsy. So we assume GME and treat it as such. Lola was diagnosed last Nov. Most of what you read on the internet says GME dogs live weeks to a few months. There are new treatment protocols out there that are making a big difference. Still a tough disease to treat. Something Dr. Sullivan said to me really made sense to me. She said "Dogs don't understand length of life. they only understand quality"
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Pam, i'm praying that the meds work for Lola.:prayer:
Oh Pam.....I am so sorry that Lola is still not feeling well. Maybe the prednisone will help her, along with anything else Dr Sullivan wants to use. Believe me, I understand about the quality of life, I have always made the decision, Heath, my husband cannot. Then I am left with such pain for having to do it. I pray for Lola and for you.......
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