The ALT or ASP numbers are very high, you will need diet and medication to get them down and have them rechecked in a month or so. I think it would point to an internal injury of some type or if the dog got into something toxic. It could also be a digestive problem. Dogs with shuts would not normally have enzyme values that high. Lucky's were always a few points within normal. Not always, but normally post bile acids under 100 point to MVD rather than a shunt. The next test would be a simple blood test called a protein-c which can help distinguish between a shunt and MVD. The good news is that if it is a shunt, many dogs can live a normal life with medication and diet. If is really important to find an internist that specializes in toy breeds. Let me know of any questions I can answer. Good Luck and try not to worry too much; remember the results of any blood test is a snapshot, and all sorts of things cou!d contribute to elevated values.