My darling and beautiful 4-year old Romeo has passed after a harrowing struggle with GME. He was the picture of health only two weeks ago, but then very quickly started to decline. He had difficulty walking on his back legs, wobbled and fell, had pain in his back (arched) and neck, sometimes shrieked out in pain. The first vet, quite wrong, thought it was luxating patella... The second vet, a few days later, told us to take him to a neurologist immediately, through emergency. We did so the next morning, at the excellent UC Davis Veterinary Hospital, and learned that he probably had GME or something similar. He had inflammation all along his spine and fluid in his brain, although his spinal fluid was normal, which they found confusing. They kept him for several days and, after MRIs and spinal taps were done, gave him prednisone. He responded very well, almost back to normal, running and playing, and we brought him home. But after just a few days on his moderate dose of prednisone he began to decline again, and, even after raising the dose of prednisone, there was no holding the disease back. Within a day or two, he was unable to stand up--even to pee--panting, and in pain--although he gallantly tried to rally. We drove him back to UC Davis. During the ride, he was gasping for breath. They immediately gave him oxygen. They said he was nearly blue. But it was to no avail. The neurologist said that, even with further tests (costing thousands), his prognosis was "guarded to poor." In other words, it was time to put him down, after only 4 years! I left his body for an autopsy, so that we can learn more about this horrible, frightening disease affecting our darling Maltese. My breeder thinks the MUA (or variant) came in through the Korean stud - Koko - owned by Linda McDonald - who has produced other GME dogs. Do avoid that lineage! My heart is broken for this delightful, charming, bright, affectionate little lover who brought joy to everyone. He had the most beautiful face I've ever seen in a Maltese (even the breeder agreed) and a happy, affectionate, bright personality that won all hearts. Goodbye, sweet prince, and thank you for all the love you have shown to us. You did not leave this earth without having someone who loved you very, very much.